The following information was taken from the National Institute of Health website1.
How Is Psoriasis Treated?
Doctors generally treat psoriasis in steps based on the severity of the disease, size of the areas involved, type of psoriasis, and the patient's response to initial treatments. This is sometimes called the "1-2-3" approach. In step 1, medicines are applied to the skin (topical treatment). Step 2 uses light treatments (phototherapy). Step 3 involves taking medicines by mouth or injection that treat the whole immune system (called systemic therapy).
Over time, affected skin can become resistant to treatment, especially when topical corticosteroids are used. Also, a treatment that works very well in one person may have little effect in another. Thus, doctors often use a trial-and-error approach to find a treatment that works, and they may switch treatments periodically (for example, every 12 to 24 months) if a treatment does not work or if adverse reactions occur.
Significant progress has been made in understanding the inheritance of psoriasis. A number of genes involved in psoriasis are already known or suspected. In a multifactor disease (involving genes, environment, and other factors), variations in one or more genes may produce a greater likelihood of getting the disease. Researchers are continuing to study the genetic aspects of psoriasis.
Since discovering that inflammation in psoriasis is triggered by T cells, researchers have been studying new treatments that quiet immune system reactions in the skin. Among these are treatments that block the activity of T cells or block cytokines (proteins that promote inflammation).
Recent research has suggested that psoriasis patients may be at greater risk of cardiovascular problems, especially if the psoriasis is sever, as well as obesity, high blood pressure, and diabetes. Researchers are trying to determine the reasons for these associations and how best to treat patients.
The statements contained herein have not been evaluated by the FDA. The information provided is intended to help you better understand the different treatments for the symptoms of psoriasis, eczema and seborrheic dermatitis. We attempt to provide you with accurate and current information, but make no guarantees or representations to its accuracy or completeness. Always consult your physician or other health care provider concerning your health care related questions or before starting any new health care regime. Inclusion on this website of information from others or links to other websites does not constitute the endorsement by Ontos, Inc. of the content of such other sources, nor an endorsement by those entities of the products or representation of Ontos, Inc.